“ Total Knee Replacement is an end stage procedure which should be avoided or postponed as long as possible”

Our Mission

Our mission is to make the lifetime treatment of cartilage defects sustainable by developing a joint-preserving knee resurfacing implant specifically intended for the middle-aged population.

Our Origin

Avalanche Medical BV is a spin-off from the Chemelot InSciTe public-private collaboration project SyCap which ran from 2015 until 2021. DSM Biomedical, Maastricht University, Maastricht University Medical Center, Eindhoven University of Technology, and Chemelot InSciTe participated in this project. This consortium has iteratively gone through the implant design-, development-, and evaluation process, making sure to employ proper design control in accordance with an ISO13485 certified quality management system. Risk analysis procedures (failure mode effects analysis) were carefully followed during the implant’s iterative development. Avalanche Medical’s origin is illustrative of the team’s roots in a highly-qualified network and the name of our first product pays homage to our roots.

Our Current Status

Avalanche Medical owns an exclusive license to the proprietary technology developed in the Chemelot InSciTe SyCap project. We are currently seeking funding to continue the development of the SyCap implant and to initialize clinical trials.

Our Ambition

Our ambition is to initiate a first-in-human clinical trial with the SyCap implant in 2024.